0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,779 European ancestry cases, 5,584 European ancestry controls.
The effect
Each copy of the G allele carried 1.33 times the odds of Progressive supranuclear palsy (95% confidence interval 1.25-1.41); p = 5 × 10−12.
How common The G allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 6, band 6p21.1 — in an intron of RUNX2.
What each result means
A/ANo copy of the version the research linked to Progressive supranuclear palsy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Progressive supranuclear palsy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Progressive supranuclear palsy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39251599 · open access
Questions about rs12197948
What is rs12197948?
rs12197948 is a single position in the genome, in or near the RUNX2 gene. Published research associates it with progressive supranuclear palsy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12197948 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12197948 come from?
GWAS Catalog, Nature communications 2024, PMID:39251599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.