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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 31,355 British ancestry cases, 377,103 British ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 2 × 10−10.
How common The G allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 6, band 6q23.2 — in an intron of TARID.
What each result means
A/ANo copy of the version the research linked to Ischemic heart disease (PheCode 411). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Ischemic heart disease (PheCode 411). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Ischemic heart disease (PheCode 411). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2018 · PMID 30104761 · open access
Questions about rs12194592
What is rs12194592?
rs12194592 is a single position in the genome, in or near the TARID gene. Published research associates it with ischemic heart disease (phecode 411). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12194592 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12194592 come from?
GWAS Catalog, Nature genetics 2018, PMID:30104761. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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