Gene Knowledge Graph
UTC
Standard

Tooth agenesis

WNT10A · rs121908120

Where this position leads

Condition: Tooth Agenesis

rs121908120 Condition: Tooth Agenesis Tooth Agenesis Condition rs121908120 rs121908120 WNT10A

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Tooth agenesis compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Tooth agenesis.
T/T Published research associates this genotype with typical/baseline likelihood of Tooth agenesis — no copies of the reported risk allele.
Source
Rare and Common Variants Conferring Risk of Tooth Agenesis
Jonsson L, Magnusson TE, Thordarson A, Jonsson T, Geller F, Feenstra B, Melbye M, Nohr EA, Vucic S, Vucic S, Dhamo B, Rivadeneira F
and 25 more — show all
Ongkosuwito EM, Wolvius EB, Leslie EJ, Marazita ML, Howe BJ, Moreno Uribe LM, Alonso I, Santos M, Pinho T, Jonsson R, Audolfsson G, Gudmundsson L, Nawaz MS, Olafsson S, Gustafsson O, Ingason A, Unnsteinsdottir U, Bjornsdottir G, Walters GB, Zervas M, Oddsson A, Gudbjartsson DF, Steinberg S, Stefansson H, Stefansson K
Journal of dental research · 2018 · PMID 29364747

Questions about rs121908120

What is rs121908120?

rs121908120 is a single position in the genome, in or near the WNT10A gene. Published research associates it with tooth agenesis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs121908120 linked to?

On MyGeneLog this position is linked to Tooth Agenesis. The research behind each link, and its sources, are set out on that condition page.

Does having rs121908120 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs121908120 come from?

GWAS Catalog, J Dent Res 2018, PMID:29364747. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants