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Blood protein levels

METTL24 · rs12189608

What the study found

Who was studied 3,200 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.378 higher (95% confidence interval 0.26-0.5); p = 7 × 10−10.

How common The A allele had a frequency of about 96% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of METTL24.

What each result means

A/A Two copies of the version the research linked to Blood protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Blood protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blood protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs12189608

What is rs12189608?

rs12189608 is a single position in the genome, in or near the METTL24 gene. Published research associates it with blood protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12189608 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12189608 come from?

GWAS Catalog, Science (New York, N.Y.) 2018, PMID:30072576. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Blood protein levels (rs12189608). MyGeneLog™. https://www.mygenelog.com/variants/rs12189608

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