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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 348,219 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0158 lower (95% confidence interval 0.01-0.021); p = 5 × 10−8.
Where it sits Chromosome 5, band 5q14.3 — in an intron of TMEM161B-DT.
What each result means
C/CNo copy of the version the research linked to Worry. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Worry. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Worry. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12188167 is a single position in the genome, in or near the TMEM161B-DT gene. Published research associates it with worry. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12188167 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12188167 come from?
GWAS Catalog, Nature genetics 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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