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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,748 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 12.7 z score higher; p = 5 × 10−37.
How common The C allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 5, band 5q14.2 — between genes, 227.9 kb from ATP6AP1L.
What each result means
C/CTwo copies of the version the research linked to Vertex-wise cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Vertex-wise cortical thickness. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Vertex-wise cortical thickness. This is the starting point the study compared everyone against.
Science advances · 2021 · PMID 34910505 · open access
Questions about rs12187334
What is rs12187334?
rs12187334 is a single position in the genome, in or near the near ATP6AP1L gene. Published research associates it with vertex-wise cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12187334 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12187334 come from?
GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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