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Right hippocampal volume (tail)

PCMT1 · rs12174588

What the study found

Who was studied 38,977 European ancestry, East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0594 higher (95% confidence interval 0.043-0.076); p = 2 × 10−12.

How common The C allele had a frequency of about 83% in the people studied.

Where it sits Chromosome 6, band 6q25.1 — in an intron of PCMT1.

What each result means

C/C Two copies of the version the research linked to Right hippocampal volume (tail). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Right hippocampal volume (tail). That is a smaller link than two copies.
T/T No copy of the version the research linked to Right hippocampal volume (tail). This is the starting point the study compared everyone against.
Source

Questions about rs12174588

What is rs12174588?

rs12174588 is a single position in the genome, in or near the PCMT1 gene. Published research associates it with right hippocampal volume (tail). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12174588 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12174588 come from?

GWAS Catalog, Nature genetics 2023, PMID:37337106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Right hippocampal volume (tail) (rs12174588). MyGeneLog™. https://www.mygenelog.com/variants/rs12174588

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