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Total cholesterol levels

near HLA-B · rs12173764

What the study found

Who was studied 146,492 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0322 lower (95% confidence interval 0.024-0.04); p = 5 × 10−14.

How common The T allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 7.6 kb from HLA-B.

What each result means

C/C No copy of the version the research linked to Total cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12173764

What is rs12173764?

rs12173764 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12173764 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12173764 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total cholesterol levels (rs12173764). MyGeneLog™. https://www.mygenelog.com/variants/rs12173764

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