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Insulin-like growth factor 1 levels

near RPL24P7 · rs12152551

Where this position leads

Condition: Gout

rs12152551 Condition: Gout Gout Condition rs12152551 rs12152551 near RPL24P7

What the study found

Who was studied 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0147 lower (95% confidence interval 0.0098-0.0196); p = 4 × 10−9.

Where it sits Chromosome 3, band 3p24.3 — between genes, 21.6 kb from RPL24P7.

What each result means

A/A Two copies of the version the research linked to Insulin-like growth factor 1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Insulin-like growth factor 1 levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Insulin-like growth factor 1 levels. This is the starting point the study compared everyone against.
Source

Questions about rs12152551

What is rs12152551?

rs12152551 is a single position in the genome, in or near the near RPL24P7 gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12152551 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs12152551 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12152551 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Insulin-like growth factor 1 levels (rs12152551). MyGeneLog™. https://www.mygenelog.com/variants/rs12152551

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