Standard
Thyroid volume
CAPZB · rs12138950
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Thyroid volume compared to the general population. (GWAS Catalog, Am J Hum Genet 2011, PMID:21565293)
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Thyroid volume. (GWAS Catalog, Am J Hum Genet 2011, PMID:21565293)
C/C
Published research associates this genotype with typical/baseline likelihood of Thyroid volume — no copies of the reported risk allele. (GWAS Catalog, Am J Hum Genet 2011, PMID:21565293)
Source
Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk
Teumer A,
Rawal R,
Homuth G,
Ernst F,
Heier M,
Evert M,
Dombrowski F,
Völker U,
Nauck M,
Radke D,
Ittermann T,
Biffar R
and 7 more — show all
American journal of human genetics · 2011 · PMID 21565293
Questions about rs12138950
What is rs12138950?
rs12138950 is a single position in the genome, in or near the CAPZB gene. Published research associates it with thyroid volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12138950 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12138950 come from?
GWAS Catalog, Am J Hum Genet 2011, PMID:21565293. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants