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Cortical thickness

RERE · rs12136766

What the study found

Who was studied 35,657 White British ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−11.

How common The G allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 1, band 1p36.23 — in an intron of RERE.

What each result means

A/A No copy of the version the research linked to Cortical thickness. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Cortical thickness. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12136766

What is rs12136766?

rs12136766 is a single position in the genome, in or near the RERE gene. Published research associates it with cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12136766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12136766 come from?

GWAS Catalog, NeuroImage 2021, PMID:34560273. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cortical thickness (rs12136766). MyGeneLog™. https://www.mygenelog.com/variants/rs12136766

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