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Leucine-rich repeat transmembrane protein FLRT2 levels

ADGRL2 · rs12132199

What the study found

Who was studied 2,893 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.194 higher (95% confidence interval 0.14-0.25); p = 6 × 10−12.

How common The T allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 1, band 1p31.1 — in an intron of ADGRL2.

What each result means

C/C No copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12132199

What is rs12132199?

rs12132199 is a single position in the genome, in or near the ADGRL2 gene. Published research associates it with leucine-rich repeat transmembrane protein flrt2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12132199 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12132199 come from?

GWAS Catalog, Nature communications 2021, PMID:34857772. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Leucine-rich repeat transmembrane protein FLRT2 levels (rs12132199). MyGeneLog™. https://www.mygenelog.com/variants/rs12132199

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