Standard

Triglycerides

DOCK7 · rs12130333

Where this position leads

Condition: High Triglycerides

rs12130333 Condition: High Triglycerides High Triglycerides Condition rs12130333 rs12130333 DOCK7

What the study found

Who was studied 2,758 European ancestry individuals; replicated in 18,554 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.11 lower (95% confidence interval 0.07-0.15); p = 2 × 10−8.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in an intron of DOCK7-DT.

What each result means

C/C No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12130333

What is rs12130333?

rs12130333 is a single position in the genome, in or near the DOCK7 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12130333 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs12130333?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), cholesterol and blood fats (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12130333 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12130333 come from?

GWAS Catalog, Nat Genet 2008, PMID:18193044. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs12130333). MyGeneLog™. https://www.mygenelog.com/variants/rs12130333

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