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Who was studied 33,157 Finnish ancestry cases, 199,208 Finnish ancestry controls.
The effect
Each copy of the G allele carried 1.10 times the odds of Pharyngeal disease (95% confidence interval 1.06-1.13); p = 2 × 10−10.
How common The G allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 1, band 1q41 — in an intron of LINC01705.
What each result means
A/ANo copy of the version the research linked to Pharyngeal disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Pharyngeal disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Pharyngeal disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 36653354 · open access
Questions about rs12128267
What is rs12128267?
rs12128267 is a single position in the genome, in or near the LINC01705 gene. Published research associates it with pharyngeal disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12128267 linked to?
On MyGeneLog this position is linked to Pharyngeal Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs12128267 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12128267 come from?
GWAS Catalog, Nature communications 2023, PMID:36653354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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