near KLF12 · rs12100281
Where this position leads
Condition: Hidradenitis Suppurativa
What the study found
Who was studied 3,322 European, Hispanic or Latin American, Asian or unknown ancestry cases, 1,132,141 European, Hispanic or Latin American, Asian or unknown ancestry controls.
The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−8.
How common The A allele had a frequency of about 91% in the people studied.
Where it sits Chromosome 13, band 13q22.1 — in an intron of LINC00393.
rs12100281 is a single position in the genome, in or near the near KLF12 gene. Published research associates it with hidradenitis suppurativa. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Hidradenitis Suppurativa. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, The British journal of dermatology 2025, PMID:40650879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hidradenitis suppurativa (rs12100281). MyGeneLog™. https://www.mygenelog.com/variants/rs12100281