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Serum amyloid P-component levels

near OR10AE1P · rs12079353

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.868 lower (95% confidence interval 0.61-1.13); p = 6 × 10−11.

Where it sits Chromosome 1, band 1q23.2 — between genes, 2.2 kb from OR10AE1P.

What each result means

A/A Two copies of the version the research linked to Serum amyloid P-component levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Serum amyloid P-component levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Serum amyloid P-component levels. This is the starting point the study compared everyone against.
Source

Questions about rs12079353

What is rs12079353?

rs12079353 is a single position in the genome, in or near the near OR10AE1P gene. Published research associates it with serum amyloid p-component levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12079353 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12079353 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum amyloid P-component levels (rs12079353). MyGeneLog™. https://www.mygenelog.com/variants/rs12079353

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