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Monocyte chemoattractant protein-1 levels

DARC · rs12075

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte chemoattractant protein-1 levels compared to the general population. (GWAS Catalog, Cytokine 2012, PMID:23017229)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte chemoattractant protein-1 levels. (GWAS Catalog, Cytokine 2012, PMID:23017229)

G/G Published research associates this genotype with typical/baseline likelihood of Monocyte chemoattractant protein-1 levels — no copies of the reported risk allele. (GWAS Catalog, Cytokine 2012, PMID:23017229)

Source: GWAS Catalog, Cytokine 2012, PMID:23017229

Questions about rs12075

What is rs12075?

rs12075 is a single position in the genome, in or near the DARC gene. Published research associates it with monocyte chemoattractant protein-1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12075 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12075 come from?

GWAS Catalog, Cytokine 2012, PMID:23017229. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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