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Complement C1q subcomponent subunit C levels

C1QA · rs12058824

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.577 higher (95% confidence interval 0.49-0.66); p = 2 × 10−35.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 1, band 1p36.12 — in the 5′ untranslated region of C1QA.

What each result means

A/A Two copies of the version the research linked to Complement C1q subcomponent subunit C levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Complement C1q subcomponent subunit C levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Complement C1q subcomponent subunit C levels. This is the starting point the study compared everyone against.
Source

Questions about rs12058824

What is rs12058824?

rs12058824 is a single position in the genome, in or near the C1QA gene. Published research associates it with complement c1q subcomponent subunit c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12058824 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12058824 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Complement C1q subcomponent subunit C levels (rs12058824). MyGeneLog™. https://www.mygenelog.com/variants/rs12058824

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