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Carotid intima media thickness (mean)

near LINC00670 · rs12051555

What the study found

Who was studied 43,775 European ancestry individuals, 612 Asian ancestry individuals, 291 Black individuals, 215 Mixed ancestry individuals, 292 individuals.

The effect Each copy of the A allele shifted the measure 0.083 lower (95% confidence interval 0.061-0.105); p = 6 × 10−15.

How common The A allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 17, band 17p12 — between genes, 5.2 kb from LINC00670.

What each result means

A/A Two copies of the version the research linked to Carotid intima media thickness (mean). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Carotid intima media thickness (mean). That is a smaller link than two copies.
C/C No copy of the version the research linked to Carotid intima media thickness (mean). This is the starting point the study compared everyone against.
Source

Questions about rs12051555

What is rs12051555?

rs12051555 is a single position in the genome, in or near the near LINC00670 gene. Published research associates it with carotid intima media thickness (mean). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12051555 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12051555 come from?

GWAS Catalog, Arteriosclerosis, thrombosis, and vascular biology 2022, PMID:34852643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Carotid intima media thickness (mean) (rs12051555). MyGeneLog™. https://www.mygenelog.com/variants/rs12051555

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