A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diastolic blood pressure x alcohol consumption interaction (2df test) compared to the general population. (GWAS Catalog, PLoS One 2018, PMID:29912962)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diastolic blood pressure x alcohol consumption interaction (2df test). (GWAS Catalog, PLoS One 2018, PMID:29912962)
G/GPublished research associates this genotype with typical/baseline likelihood of Diastolic blood pressure x alcohol consumption interaction (2df test) — no copies of the reported risk allele. (GWAS Catalog, PLoS One 2018, PMID:29912962)
Source: GWAS Catalog, PLoS One 2018, PMID:29912962
Questions about rs12050759
What is rs12050759?
rs12050759 is a single position in the genome, in or near the RPP25 gene. Published research associates it with diastolic blood pressure x alcohol consumption interaction (2df test). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12050759 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs12050759 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12050759 come from?
GWAS Catalog, PLoS One 2018, PMID:29912962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.