0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 650,000 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0121 lower (95% confidence interval 0.0086-0.0156); p = 4 × 10−11.
How common The C allele had a frequency of about 53% in the people studied.
Where it sits Chromosome 15, band 15q13.3 — in an intron of OTUD7A.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Body mass index compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Body mass index.
T/TPublished research associates this genotype with typical/baseline likelihood of Body mass index — no copies of the reported risk allele.
rs12050677 is a single position in the genome, in or near the OTUD7A gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12050677 linked to?
On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.
Does having rs12050677 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12050677 come from?
GWAS Catalog, Nature genetics 2024, PMID:39375568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs12050677). MyGeneLog™. https://www.mygenelog.com/variants/rs12050677