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Triglyceride levels

DR1 · rs12044883

What the study found

Who was studied 288,127 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0193 higher (95% confidence interval 0.013-0.025); p = 2 × 10−10.

How common The A allele had a frequency of about 61% in the people studied.

Where it sits Chromosome 1, band 1p22.1 — in an intron of DR1.

What each result means

A/A Two copies of the version the research linked to Triglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglyceride levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglyceride levels. This is the starting point the study compared everyone against.
Source

Questions about rs12044883

What is rs12044883?

rs12044883 is a single position in the genome, in or near the DR1 gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12044883 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12044883 come from?

GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (rs12044883). MyGeneLog™. https://www.mygenelog.com/variants/rs12044883

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