Sensitive

Diverticular disease

KIF26B · rs12041565

Where this position leads

Condition: Diverticular Disease

rs12041565 Condition: Diverticular Disease Diverticular Disease Condition rs12041565 rs12041565 KIF26B

What the study found

Who was studied 56,355 European ancestry cases, 398,413 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.05 higher (95% confidence interval 0.036-0.064); p = 1 × 10−12.

How common The T allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 1, band 1q44 — in an intron of KIF26B.

What each result means

C/C No copy of the version the research linked to Diverticular disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Diverticular disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Diverticular disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12041565

What is rs12041565?

rs12041565 is a single position in the genome, in or near the KIF26B gene. Published research associates it with diverticular disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12041565 linked to?

On MyGeneLog this position is linked to Diverticular Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs12041565 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12041565 come from?

GWAS Catalog, Cell genomics 2023, PMID:37492107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diverticular disease (rs12041565). MyGeneLog™. https://www.mygenelog.com/variants/rs12041565

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