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Hemoglobin A1c levels

CCT3 · rs12035737

What the study found

Who was studied 288,127 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0885 lower (95% confidence interval 0.078-0.099); p = 7 × 10−58.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 1, band 1q22 — inside CCT3.

What each result means

C/C No copy of the version the research linked to Hemoglobin A1c levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hemoglobin A1c levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hemoglobin A1c levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs12035737

What is rs12035737?

rs12035737 is a single position in the genome, in or near the CCT3 gene. Published research associates it with hemoglobin a1c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12035737 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12035737 come from?

GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin A1c levels (rs12035737). MyGeneLog™. https://www.mygenelog.com/variants/rs12035737

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