Who was studied 15,997 Hispanic/Latino individuals.
The effect
Each copy of the A allele shifted the measure 2.36 ms lower (95% confidence interval 1.83-2.89); p = 9 × 10−18.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 1, band 1q24.2 — in the 3′ untranslated region of NME7.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of QT interval compared to the general population.
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with QT interval.
T/TPublished research associates this genotype with typical/baseline likelihood of QT interval — no copies of the reported risk allele.
Scientific reports · 2017 · PMID 29213071 · open access
Questions about rs12035622
What is rs12035622?
rs12035622 is a single position in the genome, in or near the ATP1B1 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12035622 linked to?
On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.
Does having rs12035622 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12035622 come from?
GWAS Catalog, Sci Rep 2017, PMID:29213071. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.