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EDAR protein levels

SSBP3 · rs12024740

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.106 higher (95% confidence interval 0.089-0.123); p = 7 × 10−39.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 1, band 1p32.3 — in an intron of SSBP3.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of EDAR protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with EDAR protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of EDAR protein levels compared to the general population.
Source

Questions about rs12024740

What is rs12024740?

rs12024740 is a single position in the genome, in or near the SSBP3 gene. Published research associates it with edar protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12024740 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12024740 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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EDAR protein levels (rs12024740). MyGeneLog™. https://www.mygenelog.com/variants/rs12024740

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