Standard
IgG N-glycosylation phenotypes (multivariate analysis)
FUT6 · rs12019136
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgG N-glycosylation phenotypes (multivariate analysis) compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgG N-glycosylation phenotypes (multivariate analysis).
G/G
Published research associates this genotype with typical/baseline likelihood of IgG N-glycosylation phenotypes (multivariate analysis) — no copies of the reported risk allele.
Source
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Shen X,
Klarić L,
Sharapov S,
Mangino M,
Ning Z,
Wu D,
Trbojević-Akmačić I,
Pučić-Baković M,
Rudan I,
Polašek O,
Hayward C,
Spector TD
and 3 more — show all
Nature communications · 2017 · PMID 28878392 · open access
Questions about rs12019136
What is rs12019136?
rs12019136 is a single position in the genome, in or near the FUT6 gene. Published research associates it with igg n-glycosylation phenotypes (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12019136 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12019136 come from?
GWAS Catalog, Nat Commun 2017, PMID:28878392. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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