near SMPX · rs12012576
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 749,391 European, East Asian, Hispanic, admixed African or South Asian ancestry men; replicated in 626 Arab ancestry men, 4,056 Asian ancestry men, 4,851 African ancestry men, 7,302 Hispanic men, 15,135 South Asian ancestry men, 17,511 African American men, 57,013 East Asian ancestry men, 65,334 European ancestry men.
The effect Each copy of the G allele shifted the measure 0.0087 lower (95% confidence interval 0.006-0.0114); p = 1 × 10−10.
How common The G allele had a frequency of about 31% in the people studied.
Where it sits Chromosome X, band Xp22.12 — between genes, 36.9 kb from SMPX.
rs12012576 is a single position in the genome, in or near the near SMPX gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Genome biology 2022, PMID:36575460. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Triglyceride levels (rs12012576). MyGeneLog™. https://www.mygenelog.com/variants/rs12012576