Sensitive

Lung adenocarcinoma

BAZ1A · rs1200399

Where this position leads

Condition: EGFR Mutation-Positive Lung Adenocarcinoma

rs1200399 Condition: EGFR Mutation-Positive Lung Adenocarcinoma EGFR Mutation-Positive Lung Adenoca… Condition rs1200399 rs1200399 BAZ1A

What the study found

Who was studied 15,581 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls.

The effect Each copy of the C allele carried 0.88 times the odds of Lung adenocarcinoma (95% confidence interval 0.85-0.92); p = 3 × 10−10.

Where it sits Chromosome 14, band 14q13.2 — in an intron of BAZ1A.

What each result means

C/C Two copies of the version the research linked to Lung adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lung adenocarcinoma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lung adenocarcinoma. This is the starting point the study compared everyone against.
Source

Questions about rs1200399

What is rs1200399?

rs1200399 is a single position in the genome, in or near the BAZ1A gene. Published research associates it with lung adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1200399 linked to?

On MyGeneLog this position is linked to EGFR Mutation-Positive Lung Adenocarcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs1200399 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1200399 come from?

GWAS Catalog, Frontiers of medicine 2021, PMID:32889700. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung adenocarcinoma (rs1200399). MyGeneLog™. https://www.mygenelog.com/variants/rs1200399

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