Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2)
DENND1A · rs12000707
0 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,919 European ancestry female cases, 116,665 European ancestry female controls.
The effect
Each copy of the T allele shifted the measure 0.4 lower; p = 2 × 10−12.
Where it sits Chromosome 9, band 9q33.3 — in an intron of DENND1A.
What each result means
C/CNo copy of the version the research linked to Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Polycystic ovary syndrome in lean individuals (BMI <= 25 kg/m2). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs12000707 is a single position in the genome, in or near the DENND1A gene. Published research associates it with polycystic ovary syndrome in lean individuals (bmi <= 25 kg/m2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs12000707 linked to?
On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs12000707 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12000707 come from?
GWAS Catalog, BMC genomics 2024, PMID:38408933. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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