Standard
B cell acute lymphoblastic leukaemia (normal cytogenetics)
IKZF1 · rs11980379
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of B cell acute lymphoblastic leukaemia (normal cytogenetics) compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with B cell acute lymphoblastic leukaemia (normal cytogenetics).
T/T
Published research associates this genotype with typical/baseline likelihood of B cell acute lymphoblastic leukaemia (normal cytogenetics) — no copies of the reported risk allele.
Source
Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex
Clay-Gilmour AI,
Hahn T,
Preus LM,
Onel K,
Skol A,
Hungate E,
Zhu Q,
Haiman CA,
Stram DO,
Pooler L,
Sheng X,
Yan L
and 21 more — show all
Liu Q,
Hu Q,
Liu S,
Battaglia S,
Zhu X,
Block AW,
Sait SNJ,
Karaesmen E,
Rizvi A,
Weisdorf DJ,
Ambrosone CB,
Tritchler D,
Ellinghaus E,
Ellinghaus D,
Stanulla M,
Clavel J,
Orsi L,
Spellman S,
Pasquini MC,
McCarthy PL,
Sucheston-Campbell LE
Blood advances · 2017 · PMID 29296818
Questions about rs11980379
What is rs11980379?
rs11980379 is a single position in the genome, in or near the IKZF1 gene. Published research associates it with b cell acute lymphoblastic leukaemia (normal cytogenetics). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11980379 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11980379 come from?
GWAS Catalog, Blood Adv 2017, PMID:29296818. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants