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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 61,745 African ancestry individuals, 6,967 Asian ancestry individuals, 297,166 European ancestry individuals, 26,644 Hispanic or Latin American individuals.
The effect
Each copy of the C allele shifted the measure 0.0127 lower (95% confidence interval 0.0088-0.0166); p = 2 × 10−10.
Where it sits Chromosome 7, band 7p15.1 — in an intron of CREB5.
What each result means
C/CTwo copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 39930085 · open access
Questions about rs11980074
What is rs11980074?
rs11980074 is a single position in the genome, in or near the CREB5 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11980074 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11980074 come from?
GWAS Catalog, Nature genetics 2025, PMID:39930085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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