Standard

Systolic blood pressure

near RNA5SP188 · rs11948635

Where this position leads

Condition: Blood Pressure

rs11948635 Condition: Blood Pressure Blood Pressure Condition rs11948635 rs11948635 near RNA5SP1…

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0104 lower (95% confidence interval 0.0075-0.0133); p = 4 × 10−12.

Where it sits Chromosome 5, band 5q21.1 — between genes, 79 kb from RNA5SP188.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs11948635

What is rs11948635?

rs11948635 is a single position in the genome, in or near the near RNA5SP188 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11948635 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11948635 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11948635 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs11948635). MyGeneLog™. https://www.mygenelog.com/variants/rs11948635

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