Standard

Post bronchodilator FEV1/FVC ratio

near KRT18P51 · rs11938745

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs11938745 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs11938745 rs11938745 near KRT18P51

What the study found

Who was studied 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals.

The effect Each copy of the T allele shifted the measure 0.017 lower; p = 1 × 10−17.

How common The T allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 4, band 4q31.21 — between genes, 27.6 kb from KRT18P51.

What each result means

C/C No copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11938745

What is rs11938745?

rs11938745 is a single position in the genome, in or near the near KRT18P51 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11938745 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs11938745 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11938745 come from?

GWAS Catalog, BMC genetics 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Post bronchodilator FEV1/FVC ratio (rs11938745). MyGeneLog™. https://www.mygenelog.com/variants/rs11938745

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