Standard

Urate levels

RBM6 · rs11916261

Where this position leads

Condition: Gout

rs11916261 Condition: Gout Gout Condition rs11916261 rs11916261 RBM6

What the study found

Who was studied 342,087 European ancestry individuals, 6,011 African ancestry individuals, 7,328 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0401 higher (95% confidence interval 0.032-0.049); p = 1 × 10−20.

Where it sits Chromosome 3, band 3p21.31 — in an intron of RBM6.

What each result means

A/A Two copies of the version the research linked to Urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Urate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Urate levels. This is the starting point the study compared everyone against.
Source

Questions about rs11916261

What is rs11916261?

rs11916261 is a single position in the genome, in or near the RBM6 gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11916261 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs11916261 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11916261 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urate levels (rs11916261). MyGeneLog™. https://www.mygenelog.com/variants/rs11916261

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