Sensitive

Prostate cancer

TMPRSS2 · rs11911661

Where this position leads

Condition: Prostate Cancer

rs11911661 Condition: Prostate Cancer Prostate Cancer Condition rs11911661 rs11911661 TMPRSS2

What the study found

Who was studied 10,792 European ancestry male cases, 190,694 European ancestry male controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 8 × 10−10.

Where it sits Chromosome 21, band 21q22.3 — inside TMPRSS2.

What each result means

A/A No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11911661

What is rs11911661?

rs11911661 is a single position in the genome, in or near the TMPRSS2 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11911661 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11911661 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11911661 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs11911661). MyGeneLog™. https://www.mygenelog.com/variants/rs11911661

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