Standard
Age-related nuclear cataracts
CRYAA · rs11911275
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Age-related nuclear cataracts — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Age-related nuclear cataracts.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Age-related nuclear cataracts compared to the general population.
Source
Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract
Liao J,
Su X,
Chen P,
Wang X,
Xu L,
Li X,
Thean L,
Tan C,
Tan AG,
Tay WT,
Jun G,
Zheng Y
and 17 more — show all
Chew M,
Wang YX,
Tan QS,
Barathi VA,
Klein BE,
Saw SM,
Vithana EN,
Tai ES,
Iyengar SK,
Mitchell P,
Khor CC,
Aung T,
Wang JJ,
Jonas JB,
Teo YY,
Wong TY,
Cheng CY
Human molecular genetics · 2014 · PMID 24951543
Questions about rs11911275
What is rs11911275?
rs11911275 is a single position in the genome, in or near the CRYAA gene. Published research associates it with age-related nuclear cataracts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11911275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11911275 come from?
GWAS Catalog, Hum Mol Genet 2014, PMID:24951543. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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