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Weight

LINC01524 · rs11907932

Where this position leads

Condition: Obesity and Body Weight

rs11907932 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs11907932 rs11907932 LINC01524

What the study found

Who was studied 360,116 European ancestry individuals, 165,419 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0188 lower (95% confidence interval 0.015-0.022); p = 1 × 10−27.

Where it sits Chromosome 20, band 20q13.2 — in an intron of LINC01524.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Weight — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Weight.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Weight compared to the general population.
Source
A cross-population atlas of genetic associations for 220 human phenotypes
Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, Narita A, Konuma T, Yamamoto K, Akiyama M, Ishigaki K, Suzuki A
and 34 more — show all
Suzuki K, Obara W, Yamaji K, Takahashi K, Asai S, Takahashi Y, Suzuki T, Shinozaki N, Yamaguchi H, Minami S, Murayama S, Yoshimori K, Nagayama S, Obata D, Higashiyama M, Masumoto A, Koretsune Y, Ito K, Terao C, Yamauchi T, Komuro I, Kadowaki T, Tamiya G, Yamamoto M, Nakamura Y, Kubo M, Murakami Y, Yamamoto K, Kamatani Y, Palotie A, Rivas MA, Daly MJ, Matsuda K, Okada Y
FinnGen
Nature genetics · 2021 · PMID 34594039

Questions about rs11907932

What is rs11907932?

rs11907932 is a single position in the genome, in or near the LINC01524 gene. Published research associates it with weight. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11907932 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs11907932 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11907932 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Weight (rs11907932). MyGeneLog™. https://www.mygenelog.com/variants/rs11907932

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