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Metabolite peak levels (QI12663)

ALMS1 · rs11893881

What the study found

Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.

The effect Each copy of the A allele shifted the measure 0.205 higher (95% confidence interval 0.15-0.26); p = 1 × 10−11.

Where it sits Chromosome 2, band 2p13.1 — in an intron of ALMS1.

What each result means

A/A Two copies of the version the research linked to Metabolite peak levels (QI12663). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Metabolite peak levels (QI12663). That is a smaller link than two copies.
T/T No copy of the version the research linked to Metabolite peak levels (QI12663). This is the starting point the study compared everyone against.
Source

Questions about rs11893881

What is rs11893881?

rs11893881 is a single position in the genome, in or near the ALMS1 gene. Published research associates it with metabolite peak levels (qi12663). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11893881 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11893881 come from?

GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolite peak levels (QI12663) (rs11893881). MyGeneLog™. https://www.mygenelog.com/variants/rs11893881

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