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Pancreas proton density fat fraction

near PLEKHM3 · rs11893393

What the study found

Who was studied 37,589 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.05 higher (95% confidence interval 0.03-0.07); p = 8 × 10−9.

How common The A allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 2, band 2q33.3 — between genes, 2.4 kb from RPL12P17.

What each result means

A/A Two copies of the version the research linked to Pancreas proton density fat fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Pancreas proton density fat fraction. That is a smaller link than two copies.
G/G No copy of the version the research linked to Pancreas proton density fat fraction. This is the starting point the study compared everyone against.
Source

Questions about rs11893393

What is rs11893393?

rs11893393 is a single position in the genome, in or near the near PLEKHM3 gene. Published research associates it with pancreas proton density fat fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11893393 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11893393 come from?

GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Pancreas proton density fat fraction (rs11893393). MyGeneLog™. https://www.mygenelog.com/variants/rs11893393

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