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Leukocyte telomere length

ACYP2 · rs11890390

What the study found

Who was studied 16,759 Singaporean Han Chinese ancestry individuals; replicated in 6,337 Singaporean Chinese ancestry individuals, up to 37,505 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.048 lower; p = 5 × 10−10.

Where it sits Chromosome 2, band 2p16.2 — in an intron of ACYP2.

What each result means

C/C Two copies of the version the research linked to Leukocyte telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Leukocyte telomere length. That is a smaller link than two copies.
T/T No copy of the version the research linked to Leukocyte telomere length. This is the starting point the study compared everyone against.
Source

Questions about rs11890390

What is rs11890390?

rs11890390 is a single position in the genome, in or near the ACYP2 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11890390 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11890390 come from?

GWAS Catalog, Nature communications 2019, PMID:31171785. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Leukocyte telomere length (rs11890390). MyGeneLog™. https://www.mygenelog.com/variants/rs11890390

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