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Age at first birth

SOX11 · rs11887646

What the study found

Who was studied 542,901 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0707 lower (95% confidence interval 0.049-0.093); p = 2 × 10−10.

How common The A allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 2, band 2p25.2 — between genes, 50 kb from SOX11.

What each result means

A/A Two copies of the version the research linked to Age at first birth. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Age at first birth. That is a smaller link than two copies.
G/G No copy of the version the research linked to Age at first birth. This is the starting point the study compared everyone against.
Source

Questions about rs11887646

What is rs11887646?

rs11887646 is a single position in the genome, in or near the SOX11 gene. Published research associates it with age at first birth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11887646 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11887646 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:34211149. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Age at first birth (rs11887646). MyGeneLog™. https://www.mygenelog.com/variants/rs11887646

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