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Interferon lambda-3 levels

IFNL4 · rs11882871

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.165 lower (95% confidence interval 0.12-0.21); p = 6 × 10−11.

How common The G allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 19, band 19q13.2 — in the 3′ untranslated region of IFNL4.

What each result means

A/A No copy of the version the research linked to Interferon lambda-3 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Interferon lambda-3 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Interferon lambda-3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11882871

What is rs11882871?

rs11882871 is a single position in the genome, in or near the IFNL4 gene. Published research associates it with interferon lambda-3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11882871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11882871 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Interferon lambda-3 levels (rs11882871). MyGeneLog™. https://www.mygenelog.com/variants/rs11882871

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