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Hemoglobin concentration

PRR12 · rs11878568

Where this position leads

Condition: Blood Cell Counts

rs11878568 Condition: Blood Cell Counts Blood Cell Counts Condition rs11878568 rs11878568 PRR12

What the study found

Who was studied 746,431 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−31.

How common The C allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — in an intron of PRR12.

What each result means

C/C Two copies of the version the research linked to Hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hemoglobin concentration. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hemoglobin concentration. This is the starting point the study compared everyone against.
Source

Questions about rs11878568

What is rs11878568?

rs11878568 is a single position in the genome, in or near the PRR12 gene. Published research associates it with hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11878568 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs11878568 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11878568 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hemoglobin concentration (rs11878568). MyGeneLog™. https://www.mygenelog.com/variants/rs11878568

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