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C-reactive protein levels or HDL-cholesterol levels (pleiotropy)

LIPG · rs11874381

Where this position leads

Condition: C-Reactive Protein Levels

rs11874381 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs11874381 rs11874381 LIPG

What the study found

Who was studied 65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol).

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−15.

Where it sits Chromosome 18, band 18q21.1 — in an intron of LOC105372112.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels or HDL-cholesterol levels (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to C-reactive protein levels or HDL-cholesterol levels (pleiotropy). That is a smaller link than two copies.
G/G No copy of the version the research linked to C-reactive protein levels or HDL-cholesterol levels (pleiotropy). This is the starting point the study compared everyone against.
Source

Questions about rs11874381

What is rs11874381?

rs11874381 is a single position in the genome, in or near the LIPG gene. Published research associates it with c-reactive protein levels or hdl-cholesterol levels (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11874381 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs11874381 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11874381 come from?

GWAS Catalog, BMC Genomics 2016, PMID:27286809. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels or HDL-cholesterol levels (pleiotropy) (rs11874381). MyGeneLog™. https://www.mygenelog.com/variants/rs11874381

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