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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,476 Japanese ancestry individuals; replicated in 3,279 Japanese ancestry individuals.
The effect
Each copy of the C allele carried 1.43 times the odds of Myopic maculopathy (95% confidence interval 1.30-1.59); p = 2 × 10−12.
How common The C allele had a frequency of about 42% in the people studied.
Where it sits Chromosome 18, band 18q22.1 — between genes, 2.1 kb from LOC124904376.
What each result means
A/ANo copy of the version the research linked to Myopic maculopathy. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Myopic maculopathy. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Myopic maculopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29725004 · open access
Questions about rs11873439
What is rs11873439?
rs11873439 is a single position in the genome, in or near the CCDC102B gene. Published research associates it with myopic maculopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11873439 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11873439 come from?
GWAS Catalog, Nat Commun 2018, PMID:29725004. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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