Standard
HDL cholesterol
STARD3 · rs11869286
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of HDL cholesterol compared to the general population. (GWAS Catalog, Nature 2010, PMID:20686565)
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with HDL cholesterol. (GWAS Catalog, Nature 2010, PMID:20686565)
G/G
Published research associates this genotype with typical/baseline likelihood of HDL cholesterol — no copies of the reported risk allele. (GWAS Catalog, Nature 2010, PMID:20686565)
Source
Biological, clinical and population relevance of 95 loci for blood lipids
Teslovich TM,
Musunuru K,
Smith AV,
Edmondson AC,
Stylianou IM,
Koseki M,
Pirruccello JP,
Ripatti S,
Chasman DI,
Willer CJ,
Johansen CT,
Fouchier SW
and 197 more — show all
Isaacs A,
Peloso GM,
Barbalic M,
Ricketts SL,
Bis JC,
Aulchenko YS,
Thorleifsson G,
Feitosa MF,
Chambers J,
Orho-Melander M,
Melander O,
Johnson T,
Li X,
Guo X,
Li M,
Shin Cho Y,
Jin Go M,
Jin Kim Y,
Lee JY,
Park T,
Kim K,
Sim X,
Twee-Hee Ong R,
Croteau-Chonka DC,
Lange LA,
Smith JD,
Song K,
Hua Zhao J,
Yuan X,
Luan J,
Lamina C,
Ziegler A,
Zhang W,
Zee RY,
Wright AF,
Witteman JC,
Wilson JF,
Willemsen G,
Wichmann HE,
Whitfield JB,
Waterworth DM,
Wareham NJ,
Waeber G,
Vollenweider P,
Voight BF,
Vitart V,
Uitterlinden AG,
Uda M,
Tuomilehto J,
Thompson JR,
Tanaka T,
Surakka I,
Stringham HM,
Spector TD,
Soranzo N,
Smit JH,
Sinisalo J,
Silander K,
Sijbrands EJ,
Scuteri A,
Scott J,
Schlessinger D,
Sanna S,
Salomaa V,
Saharinen J,
Sabatti C,
Ruokonen A,
Rudan I,
Rose LM,
Roberts R,
Rieder M,
Psaty BM,
Pramstaller PP,
Pichler I,
Perola M,
Penninx BW,
Pedersen NL,
Pattaro C,
Parker AN,
Pare G,
Oostra BA,
O'Donnell CJ,
Nieminen MS,
Nickerson DA,
Montgomery GW,
Meitinger T,
McPherson R,
McCarthy MI,
McArdle W,
Masson D,
Martin NG,
Marroni F,
Mangino M,
Magnusson PK,
Lucas G,
Luben R,
Loos RJ,
Lokki ML,
Lettre G,
Langenberg C,
Launer LJ,
Lakatta EG,
Laaksonen R,
Kyvik KO,
Kronenberg F,
König IR,
Khaw KT,
Kaprio J,
Kaplan LM,
Johansson A,
Jarvelin MR,
Janssens AC,
Ingelsson E,
Igl W,
Kees Hovingh G,
Hottenga JJ,
Hofman A,
Hicks AA,
Hengstenberg C,
Heid IM,
Hayward C,
Havulinna AS,
Hastie ND,
Harris TB,
Haritunians T,
Hall AS,
Gyllensten U,
Guiducci C,
Groop LC,
Gonzalez E,
Gieger C,
Freimer NB,
Ferrucci L,
Erdmann J,
Elliott P,
Ejebe KG,
Döring A,
Dominiczak AF,
Demissie S,
Deloukas P,
de Geus EJ,
de Faire U,
Crawford G,
Collins FS,
Chen YD,
Caulfield MJ,
Campbell H,
Burtt NP,
Bonnycastle LL,
Boomsma DI,
Boekholdt SM,
Bergman RN,
Barroso I,
Bandinelli S,
Ballantyne CM,
Assimes TL,
Quertermous T,
Altshuler D,
Seielstad M,
Wong TY,
Tai ES,
Feranil AB,
Kuzawa CW,
Adair LS,
Taylor HA Jr,
Borecki IB,
Gabriel SB,
Wilson JG,
Holm H,
Thorsteinsdottir U,
Gudnason V,
Krauss RM,
Mohlke KL,
Ordovas JM,
Munroe PB,
Kooner JS,
Tall AR,
Hegele RA,
Kastelein JJ,
Schadt EE,
Rotter JI,
Boerwinkle E,
Strachan DP,
Mooser V,
Stefansson K,
Reilly MP,
Samani NJ,
Schunkert H,
Cupples LA,
Sandhu MS,
Ridker PM,
Rader DJ,
van Duijn CM,
Peltonen L,
Abecasis GR,
Boehnke M,
Kathiresan S
Nature · 2010 · PMID 20686565 · open access
Questions about rs11869286
What is rs11869286?
rs11869286 is a single position in the genome, in or near the STARD3 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11869286 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11869286 come from?
GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants