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Hyperthyroidism

MAFTRR · rs11865979

What the study found

Who was studied 6,442 European ancestry cases, 736,566 European ancestry controls.

The effect Each copy of the C allele carried 1.16 times the odds of Hyperthyroidism (95% confidence interval 1.12-1.21); p = 2 × 10−13.

Where it sits Chromosome 16, band 16q23.2 — in an intron of MAFTRR.

What each result means

C/C Two copies of the version the research linked to Hyperthyroidism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hyperthyroidism. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hyperthyroidism. This is the starting point the study compared everyone against.
Source

Questions about rs11865979

What is rs11865979?

rs11865979 is a single position in the genome, in or near the MAFTRR gene. Published research associates it with hyperthyroidism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11865979 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11865979 come from?

GWAS Catalog, European journal of endocrinology 2024, PMID:39067062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hyperthyroidism (rs11865979). MyGeneLog™. https://www.mygenelog.com/variants/rs11865979

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