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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 137 Japanese ancestry cases, 1,174 Japanese ancestry controls; replicated in 183 Japanese ancestry cases, 2,071 Japanese ancestry controls.
The effect
Each copy of the A allele carried 2.10 times the odds of Chronic central serous retinopathy (95% confidence interval 1.62-2.67); p = 1 × 10−8.
Where it sits Chromosome 16, band 16q24.2 — in an intron of SLC7A5.
What each result means
A/ATwo copies of the version the research linked to Chronic central serous retinopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Chronic central serous retinopathy. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Chronic central serous retinopathy. This is the starting point the study compared everyone against.
rs11865049 is a single position in the genome, in or near the SLC7A5 gene. Published research associates it with chronic central serous retinopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11865049 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11865049 come from?
GWAS Catalog, Invest Ophthalmol Vis Sci 2018, PMID:30480742. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Chronic central serous retinopathy (rs11865049). MyGeneLog™. https://www.mygenelog.com/variants/rs11865049