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Medication use (HMG CoA reductase inhibitors)

BCL7C · rs11864054

Where this position leads

Condition: Medication Use as a Genetic Trait

rs11864054 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs11864054 rs11864054 BCL7C

What the study found

Who was studied 73,475 European ancestry cases, 216,910 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0349 lower (95% confidence interval 0.023-0.046); p = 2 × 10−9.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 16, band 16p11.2 — in the 3′ untranslated region of BCL7C.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Medication use (HMG CoA reductase inhibitors) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (HMG CoA reductase inhibitors).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (HMG CoA reductase inhibitors) compared to the general population.
Source

Questions about rs11864054

What is rs11864054?

rs11864054 is a single position in the genome, in or near the BCL7C gene. Published research associates it with medication use (hmg coa reductase inhibitors). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11864054 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs11864054 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11864054 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (HMG CoA reductase inhibitors) (rs11864054). MyGeneLog™. https://www.mygenelog.com/variants/rs11864054

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